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Infant Acceptance of a Bitter-Tasting Liquid Medication: A Randomized Controlled Trial Comparing the Rx Medibottle With an Oral Syringe
Murli U. Purswani, MD;
Jolly Radhakrishnan, MD;
Khudsia R. Irfan, MD;
Cynthia Walter-Glickman, MA, DTR;
Stefan Hagmann, MD;
Richard Neugebauer, PhD
Arch Pediatr Adolesc Med. 2009;163(2):186-188.
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The calibrated oral syringe is considered the standard system for administering liquid formulations of medications to infants.1-2 Medication acceptance using the syringe may not always be favorable, particularly with unpleasant-tasting liquids. The Rx Medibottle (The Medicine Bottle Co, Hinsdale, Illinois), an alternate drug-delivery device, is an infant-feeding bottle that contains a central sleeve within its body into which a syringe is inserted (Figure). Depressing the syringe's plunger in quick, short squirts synchronized with an infant's sucking allows drug ingestion, preventing dilution of the drug in the formula within the bottle's nipple. The Rx Medibottle costs $14.95 retail. Kraus et al3-4 demonstrated that it was more efficacious, with a higher level of infant acceptance compared with the syringe, when used to administer a 1-time dose of a pleasant-tasting . . . [Full Text of this Article]Methods
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