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The Association Between Caregiver Knowledge of Antiretroviral Therapy Regimens and Disease Parameters Among Perinatally Human Immunodeficiency Virus–Infected Children
Ouzama Nicholson, MD, MS;
Claude Mellins, PhD;
Curtis Dolezal, PhD;
E. Karina Santamaria, BA;
Elizabeth Brackis-Cott, PhD;
Elaine J. Abrams, MD
Arch Pediatr Adolesc Med. 2006;160(12):1307-1308.
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The ability of caregivers of human immunodeficiency virus (HIV)–infected children to correctly identify or describe their child's antiretroviral therapy (ART) regimen has been associated with higher levels of ART adherence.1-2 We hypothesized that children whose caregivers could correctly describe their ART regimens would also have better HIV disease parameters as measured by CD4 percentage and HIV viral load.
Methods
Children (aged 3-13 years) and their caregivers were recruited for a cross-sectional study examining factors associated with child ART medication adherence.3-4 During a 90-minute interview, caregivers were asked to describe their child's ART regimen and comparisons were made with the medical and/or pharmacy records. Knowledge of medication regimens was defined as the percentage of antiretroviral medications reported in the medical or pharmacy record that was correctly named or whose appearance was . . . [Full Text of this Article] Results
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