Denouement and Discussion: Pityriasis Lichenoides et Varioliformis Acuta
Pityriasis lichenoides is an erythematous, papulosquamous, T-cellmediated dermatosis.1 Both acute and chronic forms are described and represent the extremes of a continuous spectrum.1 Pityriasis lichenoides et varioliformis acuta (PLEVA) refers to the acute form.
EPIDEMIOLOGY
It is a common disorder. It occurs most often during the second and third decades of life.2 There is a slight male predominance.2
ETIOLOGY AND PATHOGENESIS
An immunologically mediated reaction to an infectious agent is suspected to be the cause because sporadic outbreaks are common, and the disease has been reported to occur simultaneously among family members.2 An infection-mediated cause is also suggested by reports of PLEVA following infection with specific pathogens, by the isolation of specific pathogens coincidental with the disease, and by the presence of elevated serum titers to specific pathogens.2 Epstein-Barr virus, parvovirus, human immunodeficiency virus, group A
-hemolytic streptococci, and Toxoplasma gondii are the organisms most frequently reported in association with PLEVA.3-5
Monoclonal T-cell receptor . . . [Full Text of this Article]
CLINICAL MANIFESTATIONS
COMPLICATIONS
HISTOPATHOLOGY
DIAGNOSIS AND DIFFERENTIAL DIAGNOSIS
TREATMENT
AUTHOR INFORMATION