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Use of Intravenous Methohexital as a Sedative in Pediatric Emergency Departments
Hanan Sedik, MD
Arch Pediatr Adolesc Med. 2001;155:665-668.
Objective To evaluate the effectiveness and safety of intravenous methohexital
as a sedative in children undergoing emergency computed tomographic scans.
Design Case series.
Setting An urban pediatric emergency department at a level I trauma center.
Participants Patients receiving intravenous methohexital for sedation to undergo
emergency computed tomographic scans.
Methods Descriptive data were generated, including demographics, doses administered,
times of sedation, outcomes, and complications.
Results Data are reported from a total of 55 patients. The doses administered
ranged from 0.5 mg/kg to 2.0 mg/kg (mean ± SD, 1 ± 0.5 mg/kg).
Onset of sedation was rapid (mean ± SD, 1 ± 0.4 minutes), sedation
was brief (mean ± SD, 12 ± 5 minutes), and the mean ±
SD length of the drug's effects was 14 ± 6 minutes. Sedation was effective
in most cases, and only a few patients had complications.
Conclusion Intravenous methohexital is a short-acting and effective sedative for
use in pediatric emergency departments to obtain computed tomographic scans.
From the Division of Pediatric Emergency Medicine, Henry Ford Hospital,
Detroit, Mich. Hanan Sedik, MD, is now at the Division of Pediatric Emergency
Medicine, Boston Medical Center, and at the Department of Pediatrics, Boston
University School of Medicine, Boston, Mass.
Corresponding author and reprints: Hanan Sedik, MD, Division of Pediatric
Emergency Medicine, Boston Medical Center, 91 E Concord St, Maternity 6, Boston,
MA 02169 (e-mail: Hanan.Sedik{at}bmc.org).
THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES
Review of Pediatric Sedation
Cravero and Blike
Anesth. Analg. 2004;99:1355-1364.
ABSTRACT
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